Trace amine associated receptor 1 modulates behavioral effects of ethanol.

Few treatment options for alcohol use disorders (AUDs) exist and more are critically needed. Here, we assessed whether trace amine associated receptor 1 (TAAR1), a modulator of brain monoamine systems, is involved in the behavioral and reinforcement-related effects of ethanol and whether it could potentially serve as a therapeutic target.

Wild-type (WT) and TAAR1 knockout (KO) mice (75% C57J