Altered Neural Processing of Threat in Alcohol-Dependent Men

Stress-response biological systems are altered in alcohol-dependent individuals and are reported to predict future relapse. This study was designed to assess neural disruptions in alcohol-dependent participants when exposed to a conditioned stimulus (CS) warning of the impending onset of a universal, nonpersonalized stressor.



Fifteen alcohol-dependent men abstinent for 3 to 5 weeks and 15