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Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent.

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We have previously reported a top-ranked risk gene [i.e., serine incorporator 2 gene (SERINC2)] for alcohol dependence in individuals of European descent by analyzing the common variants in a genome-wide association study. In the present study, we comprehensively examined the rare variants [minor allele frequency ] in the NKAIN1-SERINC2 region to confirm our previous finding.

A discovery

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