Genome-wide association studies of maximum number of drinks

Maximum number of drinks (MaxDrinks) defined as “Maximum number of alcoholic drinks consumed in a 24-h period” is an intermediate phenotype that is closely related to alcohol dependence (AD). Family, twin and adoption studies have shown that the heritability of MaxDrinks is approximately 0.5.

We conducted the first genome-wide association (GWA) study and meta-analysis of MaxDrinks as a