Female Rats Display Enhanced Rewarding Effects of Ethanol That Are Hormone Dependent

Ethanol (EtOH) abuse is a major health and economic concern, particularly for females who appear to be more sensitive to the rewarding effects of EtOH. This study compared sex differences to the rewarding and aversive effects of EtOH using place-conditioning procedures in rats.



Separate groups of adult (male, female, ovariectomized [OVX] female) and adolescent (male and female) rats